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Regression of a Large Endometrio...
Endometriosis is defined as presence of endometrial glands and stroma outside endomoetrium [1]. Ovarian endometriomas are a common presentation of endometriosis. Surgery is universally considered the first therapeutic approach for women with symptomatic or enlarging endometriomas [2,3] but it may have side effect on ovarian reserve. Dienogest (DNG) is an orally-active semisynthetic, steroidal progestogen, highly selective for progesterone receptors, derivative of 19-nortestosterone, that has recently been introduced for the treatment of endometriosis. Clinical studies of DNG with durations between 12 and 24 weeks have provided information on optimal dosing and on efficacy and safety characteristics that are relevant to the long-term management of endometriosis [4-6]. However, there are few studies that show a long term treatment over 53 weeks [7]. An over 90 weeks treatment with DNG 2mg per day in our case report resulted in a remarkable regression of endometrioma and elimination of symptoms.
Mar 7, 2021 Hosted By, Medevista Official
Clinical experience of long term...
The pathology called “endometriosis is defined as presence of endometrial tissue (gland and stroma) outside the uterus”. It is the leading cause of disability in women of reproductive age, and is also said to impair the quality of life [1,2]. Endometriosis is estimated to affect 10% women in the reproductive age group [3]. Ovarian endometriosis is one of the most frequent manifestation of the disease, and previous studies indicate that 55% of women with ovarian endometriosis have endometriomas [4]. European Society of Human Reproduction and Embryology (ESHRE) guidelines state that surgical treatment would be warranted for ovarian endometriomas >3 cm. Laparoscopic stripping of the cyst wall is considered as the “Gold Standard” treatment of endometrioma as that procedure has been associated with reduced relapse rate, diminished signs and symptoms, improved intimate relations and also, improves fertility by enhancing chances of spontaneous conception.
Mar 7, 2021 Hosted By, Medevista Official
Study of dienogest for dysmenorr...
Dysmenorrhea is the most common symptom in patients with endometriosis [1]. Endometriosis is defined as the presence of endometrial glands and stroma outside the uterus. It is a chronic gynecologic disease. Symptoms include chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility in reproductive-age women.
Mar 7, 2021 Hosted By, Medevista Official
Reduced pelvic pain in women wit...
Purpose To investigate the eYcacy and safety of dienogest as a long-term treatment in endometriosis, with follow-up after treatment discontinuation. The study included women with endometriosis, who had previously completed a 12-week, placebo-controlled study of dienogest, who participated in an open-label extension study for up to 53 weeks. Thereafter,a patient subgroup was evaluate
Mar 8, 2021 Hosted By, Medevista Official
Dienogest Versus Leuprolide Acet...
Endometriosis is defined as the presence of ectopic endometrial tissue outside the uterine cavity inducing a chronic inflammatory reaction [1]. It is a common condition affecting adult women, and the exact prevalence of which is unknown but estimated to range from 2 to 10% of the general female population and up to 50% of infertile women [2]. The prevalence of endometriosis in adolescents undergoing laparoscopy for pelvic pain was reported to be 47% [3]. Although some patients with endometriosis suffer from painful symptoms and/or infertility, others are asymptomatic. Diagnosis is made by physical examination, imaging techniques, and finally proved by histopathology
Mar 8, 2021 Hosted By, Medevista Official
Endometriosis
Endometriosis may be a weakening illness with highlights of inveterate inflammation. Endometriosis shows up to be one of the foremost common generous gynecological proliferations in premenopausal ladies since it is assessed that 10–15% of regenerative matured ladies endure pelvic endometriosis. The science of endometriosis is hazy. Despite its prevalence, this malady remains ineffectively caught on and currently thinks about demonstrate that there's no relationship between the degree of the illness and its symptomatology. There's no blood test accessible for the conclusion of endometriosis. Up to this point, there's no single exceptionally fruitful choice for the treatment of endometriosis. Due to the moderately destitute adequacy of hormonal treatment for endometriosis, a few other test treatments are right now going through a trial in the clinical procedure.
Apr 22, 2021 Hosted By, Medevista Official